обобщающие работы по противовозрастным препаратам
Привет всем!
С интересом прочитал статью : Antiaging treatments have been legally
prescribed for approximately Thirty Years
Там несколько русских ученых, разбросанных по всему свету пишут что
за 30 лет применения препаратов, которые в последствии были
идентифицированны как антиэйджинговые, было проведено очень мало
исследований на тему ... как же они влияют на продолжительность жизни!
Хорошие большие исследования есть всего по нескольким препаратам.
Может кто знает, где еще можно найти такие собирательные работы или
информацию по подобным большим и достоверным исследованиям (рандомизированное,
двойное-слепое, плацебо-контролируемое, со стат. достоверной
численностью ...)?
Алексей сообщил нам о статье "Antiaging treatments have been legally
prescribed for approximately Thirty Years", но не указал источник.
Восполняю этот пробел. Реферат статьи дан ниже.
Antiaging Treatments Have Been Legally
Prescribed for Approximately Thirty Years
by
Nehlig A
Ukraintseva SV, Arbeev KG, Michalsky AI, Yashin AI.
Duke University Center for Demographic Studies,
2117 Campus Drive, Box 90408, Durham, NC 27708-0408.
ukraintse***@c*****.edu
Ann N Y Acad Sci. 2004 Jun;1019:64-69
ABSTRACT
There is an interesting divergence between the achievements of geriatrics
and gerontology. On the one hand, during the last 30 years physicians in
many developed countries have successfully prescribed several medicines to
cure various symptoms of senescence. On the other hand, the influence of
such medicines on human life span practically has not been studied. The most
common of the relevant medicines are nootropic piracetam, gamma-aminobutyric
acid (GABA), selegiline, Ginkgo biloba, pentoxifylline, cerebrolysin,
solcoseryl, ergoloid, vinpocetin, sertraline, and estrogens, among others.
Available data from human clinical practices and experimental animal studies
indicate that treatments with these drugs improve learning, memory, brain
metabolism, and capacity. Some of these drugs increase tolerance to various
stresses such as oxygen deficit and exercise, stimulate the regeneration of
neurons in the old brain, and speed up the performance of mental and
physical tasks. This means that modern medicine already has "antiaging"
treatments at its disposal. However, the influence of such treatments on the
mean and maximal life span of humans, and on the age trajectory of a human
survival curve has been poorly studied. The increase in human life
expectancy at birth in the second half of the last century was mostly caused
by the better survival at the old and oldest old rather than at the young
ages. In parallel, the consumption of brain protective and regenerative
drugs has been expanding in the elderly population. We provide evidence in
support of the idea that the consumption of medicines exerting antiaging
properties may contribute to the increase in human longevity.
За 15 долларов по адресу
http://www.annalsnyas.org/cgi/content/full/1019/1/64 вы можете получить
полный текст статьи.
Борис Кауров
Original Message From: "Алексей Потапов" <immor***@b*****.ru>
To: "science.health.ageing.antiageing (1682024)" <bok***@m*****.ru>
Sent: Thursday, May 03, 2007 7:03 AM